ABOUT GENETIC METHYLATION TEST GARY BREAKA

from the human genome, 5mC is frequently located in CpG dinucleotides, Using these sites being hotspots for mutations together with in tumor suppressor genes. by way of example, CpG island (CGI) mutations throughout the coding region of p53, a gene involved with genome stabilization and mobile cycle/apoptotic responses, lead to ~twenty five% of its